Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 7/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114288 | 0.84 | HDAC6 (0.49) | CYP11B2CYP11B1HTR3AHSPA8EGFR | |
| SCHEMBL7114061 | 0.80 | CYP11B2 (0.34) | CYP11B2CYP11B1HTR3ASLC15A1KDM4E | |
| SCHEMBL7213111 | 0.77 | HDAC6 (0.50) | SLC15A1HSPA8ADKPNP | |
| SCHEMBL7114052 | 0.75 | HDAC6 (0.49) | HSPA8EGFR | |
| SCHEMBL7739913 | 0.75 | SLC15A1 (0.38) | CYP11B2SLC15A1HSPA8ADK | |
| SCHEMBL7113026 | 0.72 | CYP11B2 (0.35) | CYP11B2CYP11B1HTR3APDE2APDE10A | |
| SCHEMBL7111753 | 0.71 | USP2 (0.39) | KDM4E | |
| SCHEMBL7742269 | 0.69 | HDAC6 (0.43) | SLC15A1ADK | |
| SCHEMBL7742274 | 0.69 | HDAC6 (0.43) | SLC15A1ADK | |
| SCHEMBL7119690 | 0.65 | HDAC6 (0.60) | SLC15A1HSPA8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | claimed |
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |