Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740617 | 0.89 | PTGES (0.36) | CDK5CDK5R1RAB9AMAOBTYMS | |
| SCHEMBL7742769 | 0.82 | APP (0.39) | APPCDK5CDK5R1AKR1C3AKR1C2 | |
| SCHEMBL6929177 | 0.82 | CDK5 (0.39) | CDK5CDK5R1KIF11 | |
| SCHEMBL7739895 | 0.81 | AKR1C3 (0.36) | APPCDK5CDK5R1RAB9AAKR1C3 | |
| SCHEMBL7735087 | 0.80 | NTRK1 (0.35) | RAB9A | |
| SCHEMBL7739643 | 0.79 | GSK3B (0.37) | — | |
| Nitrogen SCHEMBL27548156 | 0.77 | CDK5 (0.36) | CDK5CDK5R1 | |
| SCHEMBL6928596 | 0.76 | GRIN2D (0.33) | — | |
| SCHEMBL6928527 | 0.76 | PARP1 (0.40) | — | |
| SCHEMBL7741117 | 0.75 | PRKAG1 (0.37) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420386-B1 | SPINAL TRAUMATISM, EPILEPSY, CHRONIC NEURODEGENERATIVE DISEASES SUCH AS ALZHEIMER'S DISEASE, SCHIZOPHRENIA, LATERAL AMYOTROPHIC SCLEROSIS OR HUNTINGTON'S CHOREA. | LES LABORATORIES SERVIER (FR) | 2002-07-16 | — | — | US | disclosed |