SCHEMBL7740190

SCHEMBL7740190

Oc1ccc(Oc2c[c]c(F)cc2Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
STK39 Q9UEW8 1/20 0.40
MAPK1 P28482 1/20 0.40
F2 P00734 1/20 0.37
F10 P00742 1/20 0.37
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
LTA4H P09960 2/20 0.36
NR1H2 P55055 1/20 0.36
BAX Q07812 1/20 0.36
HSP90AA1 P07900 1/20 0.34
NPBWR1 P48145 1/20 0.34
MCHR1 Q99705 1/20 0.34
PNLIP P16233 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7740050 0.84 RAB9A (0.38) MEN1KMT2AMAPK1LTA4HNPBWR1
SCHEMBL7740258 0.83 STK39 (0.44) ESR1ESR2STK39F2F10
SCHEMBL7747655 0.77 AR (0.40) MEN1KMT2AESR1ESR2
SCHEMBL7745226 0.77 GSTP1 (0.39)
SCHEMBL7744203 0.76 STK39 (0.41) KMT2ASTK39HSP90AA1
SCHEMBL7740125 0.74 GAA (0.46) MAPK1
SCHEMBL7740084 0.74 MAPT (0.42) MEN1KMT2AMAPK1
SCHEMBL9623553 0.73 MEN1 (0.52) MEN1KMT2AESR1ESR2STK39
SCHEMBL1449739 0.73 F2 (0.53) MEN1KMT2AESR1ESR2STK39
SCHEMBL11683912 0.72 MEN1 (0.56) MEN1KMT2AESR1ESR2STK39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001009087-A1 SUBSTITUTED ARYLHYDRAZONE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-02-08 WO disclosed