Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.36 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740291 | 0.75 | CYP11B1 (0.51) | CYP19A1CYP1A2CYP3A4CYP2D6CYP11B1 | |
| SCHEMBL7736983 | 0.74 | ALDH1A1 (0.40) | CYP19A1ESR1ESR2TBXAS1 | |
| SCHEMBL9586325 | 0.70 | ALDH1A1 (0.45) | CYP1A2MAPT | |
| SCHEMBL2716739 | 0.68 | CYP11B1 (0.59) | CYP19A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31408151 | 0.68 | CYP11B1 (0.59) | CYP19A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8337928 | 0.66 | TBXAS1 (0.54) | HMOX1CYP19A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7740268 | 0.64 | ALDH1A1 (0.47) | HMOX2CYP19A1ESR1ESR2TBXAS1 | |
| SCHEMBL14829642 | 0.64 | CYP3A4 (0.55) | CYP19A1CYP3A4CYP2D6CYP2C9TBXAS1 | |
| SCHEMBL7811165 | 0.63 | RAB9A (0.44) | CYP1A2CYP3A4CYP2D6CYP2C9POLB | |
| SCHEMBL11022381 | 0.63 | CYP19A1 (0.54) | HMOX2CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37781-E1 | VIRICIDES, PROTEASE INHIBITOR | DUPONT PHARMACEUTICALS COMPANY | 2002-07-02 | — | — | US | disclosed |