SCHEMBL7740335

SCHEMBL7740335

CCC(C)C[C](CC(C)CC)Cn1ccnc1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
HMOX2 P30519 1/20 0.41
CYP19A1 P11511 4/20 0.40
ESR1 P03372 3/20 0.40
TBXAS1 P24557 4/20 0.40
FDPS P14324 1/20 0.38
ESR2 Q92731 1/20 0.36
QPCT Q16769 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7737916 0.95 ALDH1A1 (0.42) ALDH1A1HMOX2CYP19A1ESR1TBXAS1
SCHEMBL4581654 0.76 FDPS (0.47) ALDH1A1CYP19A1TBXAS1FDPSQPCT
SCHEMBL20953982 0.76 FDPS (0.47) ALDH1A1CYP19A1TBXAS1FDPSQPCT
Iodide SCHEMBL4367921 0.74 FDPS (0.46) CYP19A1TBXAS1FDPSQPCT
SCHEMBL19450970 0.73 TBXAS1 (0.52) ALDH1A1CYP19A1TBXAS1QPCTEGLN3
SCHEMBL27724975 0.73 TBXAS1 (0.52) ALDH1A1CYP19A1TBXAS1QPCTEGLN3
Sulfuric Acid SCHEMBL20853723 0.71 FDPS (0.47) ALDH1A1CYP19A1TBXAS1FDPSQPCT
SCHEMBL12391736 0.71 ALDH1A1 (0.62) ALDH1A1HMOX2CYP19A1TBXAS1FDPS
SCHEMBL11959516 0.70 TBXAS1 (0.58) CYP19A1TBXAS1QPCT
SCHEMBL10576973 0.70 HMOX2 (0.60) ALDH1A1HMOX2CYP19A1TBXAS1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE37781-E1 VIRICIDES, PROTEASE INHIBITOR DUPONT PHARMACEUTICALS COMPANY 2002-07-02 US disclosed