Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21408598 | 0.81 | MAPT (0.49) | KDM4EALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL14862508 | 0.81 | PGR (0.39) | MAPTHTTRARARARBRARG | |
| SCHEMBL24727712 | 0.79 | RARA (0.57) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL7028269 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL10653165 | 0.78 | RARA (0.39) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL10656659 | 0.78 | KDM4E (0.37) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6535545 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL17746857 | 0.75 | KDM4E (0.35) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL21408597 | 0.75 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL16291922 | 0.75 | LPL (0.39) | CA1CA2CA4CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165276-A1 | NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2023-06-01 | — | — | US | disclosed |
| US-6410678-B1 | HYDROXYL END GROUPS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1149852-A1 | AROMATIC POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE | TEIJIN LIMITED (JP) | 2001-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165276-A1 | NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES | CRY1, HRH3, CYP4F12 | KDM4E 393/4885ALDH1A1 2102/4885MAPT 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.