Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387641 | 0.84 | HDAC6 (0.35) | ALDH1A1MAPTTDP1CA12CA9 | |
| SCHEMBL9419671 | 0.84 | HDAC6 (0.35) | ALDH1A1MAPTTDP1CA12CA9 | |
| SCHEMBL9419631 | 0.84 | HDAC6 (0.35) | ALDH1A1MAPTTDP1CA12CA9 | |
| SCHEMBL7740717 | 0.80 | TDP1 (0.38) | ALDH1A1SMN1; SMN2ACSS2PRKACARPS6KB1 | |
| SCHEMBL7734321 | 0.78 | ADORA2B (0.35) | ALDH1A1CYP3A4KDM4E | |
| SCHEMBL7741960 | 0.78 | ALDH1A1 (0.34) | ALDH1A1MAPTTDP1CA12CA9 | |
| SCHEMBL7738765 | 0.75 | ALDH1A1 (0.33) | ALDH1A1MAPTTDP1 | |
| SCHEMBL8190628 | 0.73 | ALDH1A1 (0.49) | ALDH1A1HPGDSMN1; SMN2CYP3A4MAPT | |
| SCHEMBL7123962 | 0.73 | SLC15A1 (0.43) | ALDH1A1MAPTTDP1CA12CA9 | |
| SCHEMBL7209028 | 0.73 | SLC15A1 (0.43) | ALDH1A1MAPTTDP1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |