Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 12/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588915 | 0.83 | LMNA (0.31) | KDM4ELMNA | |
| SCHEMBL7741275 | 0.79 | KDM4E (0.33) | KDM4ELMNA | |
| SCHEMBL5842236 | 0.68 | TSHR (0.32) | — | |
| SCHEMBL5843335 | 0.67 | CYP11B1 (0.39) | — | |
| SCHEMBL7755895 | 0.67 | CYP11B1 (0.30) | — | |
| SCHEMBL6593244 | 0.67 | MAPT (0.38) | KDM4EPOLBALDH1A1LMNAMAPT | |
| SCHEMBL6594973 | 0.66 | MAPT (0.35) | KDM4EPOLBLMNAMAPT | |
| SCHEMBL8894491 | 0.66 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL5842676 | 0.64 | XDH (0.41) | — | |
| SCHEMBL5844428 | 0.63 | KDM4E (0.37) | KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6426318-B1 | KILLING WEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-30 | — | — | US | disclosed |