Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740965 | 0.87 | TSHR (0.49) | TSHRSMN1; SMN2RAB9ATP53NPC1 | |
| SCHEMBL7746299 | 0.86 | TSHR (0.40) | TSHRSMN1; SMN2RAB9ATP53NPC1 | |
| SCHEMBL7745478 | 0.85 | GRM2 (0.41) | TSHRSMN1; SMN2RAB9ATP53NPC1 | |
| SCHEMBL7745578 | 0.85 | TSHR (0.41) | TSHRSMN1; SMN2RAB9ATP53NPC1 | |
| SCHEMBL8363907 | 0.85 | ALDH1A1 (0.43) | TSHRSMN1; SMN2RAB9ATP53NPC1 | |
| SCHEMBL7745839 | 0.84 | TSHR (0.52) | TSHRSMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL7745936 | 0.83 | TSHR (0.41) | TSHRSMN1; SMN2RAB9ATP53NPC1 | |
| SCHEMBL7741406 | 0.82 | DRD2 (0.44) | TSHRSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL7740984 | 0.81 | TBXA2R (0.38) | TSHRSMN1; SMN2RAB9ATP53LMNA | |
| SCHEMBL7748043 | 0.78 | CYP3A4 (0.42) | TSHRSMN1; SMN2RAB9ATP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |