Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741406 | 0.91 | DRD2 (0.44) | TBXA2RDRD2TSHRMAPTALDH1A1 | |
| SCHEMBL7745936 | 0.87 | TSHR (0.41) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL7745904 | 0.84 | DRD2 (0.44) | TBXA2RDRD2MAPTALDH1A1LMNA | |
| SCHEMBL7745883 | 0.83 | AGTR1 (0.42) | MAPTALDH1A1LMNAPOLBPTGER4 | |
| SCHEMBL7746299 | 0.83 | TSHR (0.40) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL7746271 | 0.81 | TSHR (0.45) | TSHRALDH1A1LMNAPOLBRAB9A | |
| SCHEMBL7740752 | 0.81 | DRD2 (0.44) | TBXA2RDRD2TSHRMAPTALDH1A1 | |
| SCHEMBL7745478 | 0.81 | GRM2 (0.41) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL7745810 | 0.80 | AGTR1 (0.42) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL7745974 | 0.79 | DRD2 (0.42) | TBXA2RDRD2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |