Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519520 | 0.86 | KMT2A (0.51) | MAPT | |
| SCHEMBL6637953 | 0.78 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL8669796 | 0.77 | MTNR1A (0.63) | MTNR1AMTNR1B | |
| SCHEMBL7741711 | 0.76 | MTNR1A (0.59) | MTNR1AMTNR1B | |
| SCHEMBL8673938 | 0.75 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL7016797 | 0.74 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL7741712 | 0.72 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL8671940 | 0.71 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL8406900 | 0.71 | MTNR1A (0.57) | MTNR1AMTNR1B | |
| SCHEMBL8885378 | 0.70 | ALDH1A1 (0.48) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737670-B1 | Tricyclic amides, processes for their preparation, and pharmaceutical compositions containing them | ADIR (FR) | 1999-07-21 | — | — | EP | disclosed |
| EP-0737670-A1 | Tricyclic amides, processes for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-10-16 | — | — | EP | disclosed |