Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7929518 | 0.99 | LMNA (0.47) | SLC6A2SLC6A4SLC6A3LMNAADRB2 | |
| SCHEMBL7742852 | 0.88 | ADRB1 (0.38) | SLC6A2SLC6A4SLC6A3LMNAADRB2 | |
| SCHEMBL7932968 | 0.88 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3LMNAADRB2 | |
| Hydrochloric Acid SCHEMBL7935630 | 0.87 | ADRB1 (0.37) | SLC6A2SLC6A4SLC6A3LMNAADRB2 | |
| Hydrochloric Acid SCHEMBL8926109 | 0.86 | CYP3A4 (0.45) | SLC6A2SLC6A4SLC6A3LMNAADRB2 | |
| SCHEMBL7932945 | 0.85 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3LMNAADRB2 | |
| SCHEMBL7742861 | 0.78 | GABBR2 (0.42) | SLC6A2SLC6A4SLC6A3LMNATSHR | |
| Malic Acid SCHEMBL7932007 | 0.78 | KMO (0.44) | SLC6A2SLC6A4SLC6A3LMNAADRB2 | |
| SCHEMBL7932061 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3LMNAADRB1 | |
| SCHEMBL28320405 | 0.75 | ADRB2 (0.67) | SLC6A2SLC6A4SLC6A3LMNAADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743063-B1 | Use of derivatives of alpha-aminomethyl-3,4-dichlorobenzyl thioacetamide for the preparation of a medicament inhibiting the recapture of dopamine and compounds for this use | LAFON LABOR (FR) | 2002-02-13 | — | — | EP | claimed |
| US-5795915-A | PSYCHOLOGICAL DISORDERS; COGNITION ACTIVATORS | LABORATOIRE L. LAFON (FR) | 1998-08-18 | — | — | US | claimed |
| EP-0406088-B1 | (Alfa-t-butyl aminomethyl-3,4-dichlorobenzyl) thioacetamide, process for its preparation and its applications | LAFON LABOR (FR) | 1994-03-16 | — | — | EP | claimed |
| JP-3148254-A | — | — | None | — | — | JP | disclosed |
| US-6268397-B1 | ALPHA-(1-ADAMANTYLAMINOMETHYL)3,4-DICHLOROBENZYL)THIOACETAMID E AND ITS ISOMERS, AS WELL AS THE ADDITION SALTS OF THESE COMPOUNDS | LABORATOIRE. L. LAFON (FR) | 2001-07-31 | — | — | US | disclosed |
| US-6268397-B1 | ALPHA-(1-ADAMANTYLAMINOMETHYL)3,4-DICHLOROBENZYL)THIOACETAMID E AND ITS ISOMERS, AS WELL AS THE ADDITION SALTS OF THESE COMPOUNDS | LABORATOIRE. L. LAFON (FR) | 2001-07-31 | — | — | US | disclosed |
| US-5795915-A | PSYCHOLOGICAL DISORDERS; COGNITION ACTIVATORS | LABORATOIRE L. LAFON (FR) | 1998-08-18 | — | — | US | disclosed |
| US-5795915-A | PSYCHOLOGICAL DISORDERS; COGNITION ACTIVATORS | LABORATOIRE L. LAFON (FR) | 1998-08-18 | — | — | US | disclosed |
| JP-H03148254-A | (ALPHA(TERTBUTYLAMINOMETHYL)3,4-DICHLOROBENZYL)-THIOACETAMIDE, ITS PRODUCTION AND COMPOSITION CONTAINING THE SAME | LAB L LAFON SA | 1991-06-25 | — | — | JP | disclosed |
| EP-0406088-A1 | (Alfa-t-butyl aminomethyl-3,4-dichlorobenzyl) thioacetamide, process for its preparation and its applications | LABORATOIRE L. LAFON (FR) | 1991-01-02 | — | — | EP | disclosed |