Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747488 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2CNR1POLBRECQLRAB9A | |
| SCHEMBL7746911 | 0.84 | MEN1 (0.45) | SMN1; SMN2POLBRECQLRAB9AKDM4E | |
| SCHEMBL7745921 | 0.83 | MEN1 (0.41) | SMN1; SMN2POLBRECQLRAB9ANPC1 | |
| SCHEMBL7745935 | 0.80 | MEN1 (0.39) | SMN1; SMN2POLBRECQLRAB9ANPC1 | |
| SCHEMBL7741901 | 0.78 | POLB (0.44) | SMN1; SMN2POLBRECQLRAB9ANPC1 | |
| SCHEMBL7746351 | 0.76 | FEN1 (0.44) | SMN1; SMN2POLBRECQLKDM4ETP53 | |
| SCHEMBL7741914 | 0.73 | ALDH1A1 (0.54) | SMN1; SMN2POLBRECQLKDM4EMAPK1 | |
| SCHEMBL7746317 | 0.72 | MEN1 (0.43) | SMN1; SMN2POLBRECQLTP53MAPK1 | |
| SCHEMBL7746045 | 0.72 | SMN1; SMN2 (0.64) | SMN1; SMN2POLBRAB9AKDM4ENPC1 | |
| SCHEMBL7746367 | 0.72 | ALDH1A1 (0.48) | SMN1; SMN2POLBRECQLKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |