Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741914 | 0.87 | ALDH1A1 (0.54) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7746367 | 0.78 | ALDH1A1 (0.48) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7745691 | 0.76 | SMN1; SMN2 (0.47) | RECQLKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL7745921 | 0.74 | MEN1 (0.41) | RECQLKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL7746911 | 0.74 | MEN1 (0.45) | RECQLKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL7741901 | 0.74 | POLB (0.44) | RECQLKMT2AMEN1CYP3A4MAPT | |
| SCHEMBL7745852 | 0.73 | CYP3A4 (0.59) | RECQLKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL7437388 | 0.73 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL7745935 | 0.72 | MEN1 (0.39) | RECQLKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL7746317 | 0.72 | MEN1 (0.43) | RECQLKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |