Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | STK17B | O94768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743369 | 0.78 | NR1I2 (0.40) | NR1I2PDPK1DRD2DRD4DRD3 | |
| SCHEMBL7743321 | 0.77 | HTR1A (0.58) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL7740355 | 0.76 | KMT2A (0.34) | ACHE | |
| SCHEMBL7743295 | 0.73 | HTR1A (0.63) | NR1I2ACHEPDPK1DRD2DRD4 | |
| SCHEMBL27504019 | 0.64 | PDPK1 (0.40) | ACHEPDPK1 | |
| SCHEMBL9150411 | 0.64 | ACHE (0.52) | ACHEDRD2DRD4DRD3HTR1A | |
| SCHEMBL11856619 | 0.62 | ADRA1A (0.44) | DRD2DRD4DRD3ADRA1A | |
| SCHEMBL6678870 | 0.60 | MTNR1A (0.57) | NR1I2PDPK1DRD2DRD4DRD3 | |
| SCHEMBL14322492 | 0.60 | DRD2 (0.55) | PDPK1DRD2DRD4DRD3HTR1A | |
| SCHEMBL7740351 | 0.60 | HTR1A (0.42) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |