Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743321 | 0.79 | HTR1A (0.58) | HTR1AHTR2AMTNR1AMTNR1B | |
| SCHEMBL7741217 | 0.79 | MTNR1A (0.39) | ADRA1AMTNR1AMTNR1BADRA2AADRA2B | |
| SCHEMBL7735721 | 0.79 | MTNR1A (0.45) | MTNR1AMTNR1B | |
| SCHEMBL7743369 | 0.77 | NR1I2 (0.40) | ADRA1AMTNR1AMTNR1B | |
| SCHEMBL7743343 | 0.75 | MTNR1A (0.48) | MTNR1AMTNR1B | |
| SCHEMBL6635715 | 0.75 | MTNR1A (0.65) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL7741698 | 0.74 | HTR1A (0.65) | HTR1AHTR2AADRA1AMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7735712 | 0.74 | MTNR1A (0.64) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL7740360 | 0.74 | MTNR1A (0.67) | HTR1AHTR2AADRA1AMTNR1AMTNR1B | |
| SCHEMBL3288209 | 0.73 | ADRA2A (0.53) | HTR1AHTR2AADRA1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |