Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741773 | 0.90 | MTNR1A (0.65) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL7735737 | 0.83 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL7735692 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7741788 | 0.75 | MTNR1B (0.67) | MTNR1AMTNR1B | |
| SCHEMBL6635715 | 0.75 | MTNR1A (0.65) | MTNR1AMTNR1BHTR1A | |
| Hydrochloric Acid SCHEMBL7735712 | 0.74 | MTNR1A (0.64) | MTNR1AMTNR1BHTR1A | |
| SCHEMBL7743365 | 0.74 | HTR1A (0.43) | MTNR1AMTNR1BHTR1AHTR2AADRA1A | |
| SCHEMBL7741698 | 0.74 | HTR1A (0.65) | MTNR1AMTNR1BHTR1AHTR2AADRA1A | |
| SCHEMBL3288209 | 0.73 | ADRA2A (0.53) | HTR1AHTR2AADRA1AADRA2AADRA2B | |
| SCHEMBL6634512 | 0.72 | MTNR1A (0.64) | MTNR1AMTNR1BHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |