Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 20/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 19/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 19/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743413 | 0.93 | ADRA1D (0.42) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7749103 | 0.76 | ADRA1D (0.43) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7748895 | 0.71 | CCR2 (0.44) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7750602 | 0.66 | CCR2 (0.41) | ADRA1AADRA1DADRA1B | |
| SCHEMBL8143724 | 0.63 | ADRA1D (0.61) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7534012 | 0.59 | ADRA1A (0.86) | ADRA1AADRA1DADRA1B | |
| SCHEMBL8138620 | 0.59 | ADRA1D (0.53) | ADRA1AADRA1DADRA1B | |
| SCHEMBL31396115 | 0.59 | NPY5R (0.47) | — | |
| SCHEMBL8135445 | 0.58 | ADRA1D (0.45) | ADRA1AADRA1DADRA1B | |
| SCHEMBL6214008 | 0.58 | NPY5R (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001022919-A2 | SPIRO[BICYCLIC -AZACYCLOALKYL AND -CYCLOALKYL] DERIVATIVES AND USES THEREOF | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | claimed |