SCHEMBL7743635

SCHEMBL7743635

Cc1cccc(C(=O)Oc2ccc(C(=N)N)cc2)c1C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 3/20 0.48
▸ F10 P00742 2/20 0.48
▸ PLAU P00749 2/20 0.48
▸ PLG P00747 1/20 0.48
▸ PLAT P00750 1/20 0.48
▸ KLK1 P06870 1/20 0.48
▸ KLK5 Q9Y337 1/20 0.48
▸ PRSS1 P07477 11/20 0.46
▸ TMPRSS15 P98073 10/20 0.46
▸ KMT2A Q03164 2/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ LMNA P02545 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ PRSS2 P07478 1/20 0.44
▸ PRSS3 P35030 1/20 0.44
▸ FURIN P09958 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ ST14 Q9Y5Y6 1/20 0.42
▸ PARP10 Q53GL7 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10889487 0.88 KMT2A (0.56) F2F10PLAUPLGPLAT
SCHEMBL10946105 0.87 F2 (0.47) F2F10PLAUPLGPLAT
Hydrochloric Acid SCHEMBL11144929 0.87 KMT2A (0.55) F2F10PLAUPLGPLAT
Hydrochloric Acid SCHEMBL10942391 0.86 F2 (0.46) F2F10PLAUPLGPLAT
SCHEMBL10778989 0.80 MAPT (0.59) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL30631651 0.80 MAPT (0.59) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL10492954 0.79 PRSS1 (0.48) F2F10PLAUPLGPLAT
SCHEMBL10945116 0.78 ALDH1A1 (0.57) F2PLAUPRSS1TMPRSS15KMT2A
SCHEMBL10894177 0.77 MAPT (0.62) F2F10PLGKLK1KLK5
SCHEMBL7343416 0.77 MEN1 (0.62) F2F10PLAUPLGKLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785799-A4 PROCESS FOR PRODUCTION OF INHIBITED FORMS OF ACTIVATED BLOOD FACTORS COR THERAPEUTICS INC (US) 2001-11-21 — — EP disclosed
US-5770699-A ACYLATION COR THERAPEUTICS, INC. (US) 1998-06-23 — — US disclosed
EP-0785799-A1 PROCESS FOR PRODUCTION OF INHIBITED FORMS OF ACTIVATED BLOOD FACTORS COR THERAPEUTICS, INC. (US) 1997-07-30 — — EP disclosed
US-5602233-A ACTIVATION AND DEACTIVATION COR THERAPEUTICS, INC. (US) 1997-02-11 — — US disclosed
US-5589572-A Process for production of inhibited forms of activated blood factors COR THERAPEUTICS, INC. (US) 1996-12-31 — — US disclosed
US-5589571-A Process for production of inhibited forms of activated blood factors COR THERAPEUTICS, INC. (US) 1996-12-31 — — US disclosed
WO-1996013274-A1 PROCESS FOR PRODUCTION OF INHIBITED FORMS OF ACTIVATED BLOOD FACTORS COR THERAPEUTICS, INC. (US) 1996-05-09 — — WO disclosed
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