Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 5/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.37 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10128793 | 0.88 | GPR119 (0.41) | STSALDH1A1GPR119PDE4APDE4B | |
| SCHEMBL6258706 | 0.88 | L3MBTL1 (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2778449 | 0.88 | L3MBTL1 (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL760419 | 0.86 | GPR119 (0.36) | CCR5ALDH1A1GPR119PKMPDE4A | |
| SCHEMBL27685734 | 0.81 | ALDH1A1 (0.35) | CCR5ALDH1A1GPR119PKM | |
| SCHEMBL28677708 | 0.76 | JAK2 (0.46) | STSALDH1A1GPR119KDM4EPKM | |
| SCHEMBL8051176 | 0.73 | PSEN1 (0.40) | CCR5ALDH1A1GPR119BACE1 | |
| SCHEMBL6218154 | 0.72 | ALDH1A1 (0.61) | STSALDH1A1SMN1; SMN2TGFBR1GPR119 | |
| SCHEMBL7608032 | 0.70 | GPR119 (0.52) | CCR5STSTGFBR1GPR119KDM4E | |
| SCHEMBL7744117 | 0.70 | PSEN1 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742158-B2 | Protease inhibitors | TaiMed Biologies, Inc. (TW) | 2014-06-03 | — | — | US | disclosed |
| US-20130158261-A1 | PROTEASE INHIBITORS | TAIMED BIOLOGICS, INC. (TW) | 2013-06-20 | — | — | US | disclosed |
| US-8410300-B2 | Protease inhibitors | TAIMED BIOLOGICS, INC. (TW) | 2013-04-02 | — | — | US | disclosed |
| US-20100184974-A1 | Protease Inhibitors | AMBRILIA BIOPHARMA INC. (CA) | 2010-07-22 | — | — | US | disclosed |
| US-6632816-B1 | Aromatic derivatives as HIV aspartyl protease inhibitors | PHARMACOR INC. (CA) | 2003-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184974-A1 | Protease Inhibitors | PREP, CTRL, CTRB1 | CCR5 219/4885STS 916/4885ALDH1A1 2832/4885 |
| US-20130158261-A1 | PROTEASE INHIBITORS | PREP, CTRL, CTRB1 | CCR5 219/4885STS 916/4885ALDH1A1 2832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.