Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.38 |
| ▸ | RAPGEF3 | O95398 | 4/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744114 | 1.00 | KIF11 (0.39) | KIF11KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL7736234 | 0.86 | RAPGEF3 (0.38) | KIF11KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL7736233 | 0.86 | RAPGEF3 (0.38) | KIF11KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL8207246 | 0.78 | ALDH1A1 (0.40) | KIF11KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL8207243 | 0.78 | ALDH1A1 (0.40) | KIF11KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL7744122 | 0.75 | NPSR1 (0.43) | MAPTL3MBTL1RAPGEF3RAPGEF4SMN1; SMN2 | |
| SCHEMBL7744125 | 0.75 | NPSR1 (0.43) | MAPTL3MBTL1RAPGEF3RAPGEF4SMN1; SMN2 | |
| SCHEMBL7742016 | 0.74 | DDR1 (0.49) | KIF11MRGPRX4MLYCDTMPRSS4RXFP1 | |
| SCHEMBL6258551 | 0.72 | RAPGEF3 (0.38) | MAPTRAPGEF3RAPGEF4SMN1; SMN2 | |
| SCHEMBL7736249 | 0.72 | DDR1 (0.40) | KIF11KDM4EMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417386-B2 | HYDRAZONE DERIVATIVES; ACARINA; MITICIDES | SYNGENTA CROP PROTECTION, INC. | 2002-07-09 | — | — | US | disclosed |
| US-20010039247-A1 | Pesticidal compositions | KARRER FRIEDRICH (CH) | 2001-11-08 | — | — | US | disclosed |
| US-6306798-B1 | Compounds for controlling insects and representatives of the order acarina | SYNGENTA CROP PROTECTION, INC. | 2001-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039247-A1 | Pesticidal compositions | MTX1, PEF1, ECH1 | KIF11 817/4885KDM4E 4178/4885MAPT 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.