Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.46 |
| ▸ | TUBB | P07437 | 3/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28202170 | 0.80 | CA1 (0.52) | PTGS2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL8604 | 0.79 | CA2 (0.57) | CYP3A4MAPTABCB1CYP19A1AOC3 | |
| SCHEMBL7961363 | 0.77 | PTGS2 (0.64) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL7959757 | 0.77 | PTGS2 (0.64) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL911288 | 0.76 | PTGS2 (0.57) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL8853 | 0.76 | ALDH1A1 (0.46) | PTGS2ABCB1CYP19A1 | |
| SCHEMBL7744202 | 0.75 | ACHE (0.38) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL6995298 | 0.75 | CYP1A2 (0.54) | PTGS2CYP3A4MAPTTUBB1TUBB4A | |
| SCHEMBL11841088 | 0.74 | PTGS2 (0.59) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL7959754 | 0.74 | PTGS2 (0.59) | PTGS2HTR2AHTR2CHTR2BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2656 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300932-A1 | CYCLIC PEPTIDES TARGETING ALPHA-4-BETA-7 INTEGRIN | ZEALAND PHARMA A/S (DK) | 2021-09-30 | — | — | US | claimed |
| US-11072616-B2 | Cyclic peptides targeting alpha-4-beta-7 integrin | UNIVERSITE DE MONTREAL (CA) | 2021-07-27 | — | — | US | claimed |
| US-9200006-B2 | Protease inhibitors | MEDIVIR AB (SE) | 2015-12-01 | — | — | US | claimed |
| US-8618286-B2 | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON, INC. (CA) | 2013-12-31 | — | — | US | claimed |
| US-8106043-B2 | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON, INC. (CA) | 2012-01-31 | — | — | US | claimed |
| US-6677372-B2 | N-(3-benzofuranyl)urea-derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | claimed |
| EP-0882024-B1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LAB (US) | 2002-02-06 | — | — | EP | claimed |
| US-5679797-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-10-21 | — | — | US | claimed |
| US-5646121-A | CYTOMEGALOVIRUSES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-08 | — | — | US | claimed |
| US-5633231-A | CYTOMEGALOVIRUS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | claimed |
| US-5541206-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTION | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | claimed |
| EP-0362634-A2 | Basic dihydropyridines, process for their preparation and their use as intermediates | BAYER AG (DE) | 1990-04-11 | — | — | EP | claimed |
| US-4818748-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-04 | — | — | US | claimed |
| EP-0236874-A2 | Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes | BAYER AG (DE) | 1987-09-16 | — | — | EP | claimed |
| CN-118355015-A | N- (5-substituted- [ (1, 3, 4-thiadiazole) or (thiazolyl) ]) (substituted) carboxamide compounds for inhibiting human polymerase θ and uses thereof | 修复治疗公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2024148257-A1 | MDM2 TARGETING PROTACS | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2024-07-11 | — | — | WO | disclosed |
| US-4371531-A | OXIME-SUBSTITUTED ANTIBIOTICS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1983-02-01 | — | — | US | disclosed |
| US-4242510-A | Cephalosporin compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-12-30 | — | — | US | disclosed |
| EP-0000644-A2 | Lower cycloalkyl substituted-benzene derivatives, the preparation thereof and their pharmaceutical compositions | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-02-07 | — | — | EP | disclosed |