SCHEMBL7744516

SCHEMBL7744516

COCCN[C@@H](CC(=O)O)C(N)=O

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.37
TSHR P16473 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MAPK1 P28482 1/20 0.32
PTGER4 P35408 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2249270 0.83 GGH (0.40) ALDH1A1
SCHEMBL8728335 0.79 GPR84 (0.33) CA2ALOX15
SCHEMBL15636484 0.79 TDP1 (0.36) HPGDTSHRALDH1A1MAPK1PTGER4
SCHEMBL8420549 0.79 TSHR (0.33) TSHRMAPK1
SCHEMBL4553554 0.77 GABRR1 (0.32) ALDH1A1CA2CA4
SCHEMBL4030392 0.77 GABRR1 (0.32) ALDH1A1CA2CA4
SCHEMBL5144359 0.77 GABRR1 (0.32) ALDH1A1CA2CA4
SCHEMBL27902177 0.77 GGT1 (0.46) CA2CA4
SCHEMBL6945723 0.75 TSHR (0.54) HPGDTSHRALDH1A1MAPK1CA2
SCHEMBL8729461 0.75 CA2 (0.42) HPGDTSHRALDH1A1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5858244-A COPOLYMER COMPRISING AT LEAST ONE OF N-OXYGENATEDHYDROCARBONAMIDE MONOMERS AND AT LEAST ONE OF AMINO ACID MONOMERS, POLYSUCCINIMIDES NALCO CHEMICAL COMPANY (US) 1999-01-12 US claimed
US-5776875-A Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-07-07 US claimed
EP-0819653-A2 Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-01-21 EP claimed
US-6184336-B1 USEFUL AS CHELANTS IN WATER TREATMENT NALCO CHEMICAL COMPANY 2001-02-06 US disclosed
US-5929198-A HIGH MOLECULAR WEIGHT POLYMERS MODIFIED WITH N-DERIVATIZED COMPOUNDS NALCO CHEMICAL COMPANY (US) 1999-07-27 US disclosed
US-5876623-A ANTIDEPOSIT AGENT NALCO CHEMICAL COMPANY (US) 1999-03-02 US disclosed
US-5858244-A COPOLYMER COMPRISING AT LEAST ONE OF N-OXYGENATEDHYDROCARBONAMIDE MONOMERS AND AT LEAST ONE OF AMINO ACID MONOMERS, POLYSUCCINIMIDES NALCO CHEMICAL COMPANY (US) 1999-01-12 US disclosed
US-5776875-A Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-07-07 US disclosed
EP-0832851-A1 Biodegradable poly (amino acids), derivatized amino acid polymers and methods for making the same Nalco Chemical Company (US) 1998-04-01 EP disclosed
EP-0819653-A2 Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-01-21 EP disclosed