SCHEMBL8420549

SCHEMBL8420549

NC(=O)[C@H](CC(=O)O)NCCOCCO

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aspartic Acid SCHEMBL8450827 0.91 GRIK1 (0.33)
SCHEMBL4030392 0.82 GABRR1 (0.32) MEN1KMT2A
SCHEMBL5144359 0.82 GABRR1 (0.32) MEN1KMT2A
SCHEMBL4553554 0.82 GABRR1 (0.32) MEN1KMT2A
SCHEMBL7744516 0.79 HPGD (0.37) TSHRMAPK1
SCHEMBL1880686 0.79 CAMK2A (0.33)
SCHEMBL8424379 0.79 CAMK2A (0.33)
SCHEMBL8096749 0.78 CA2 (0.39) TSHRMEN1KMT2A
SCHEMBL28308288 0.77 GPR84 (0.34)
SCHEMBL29896405 0.77 CA2 (0.38) TSHRMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5858244-A COPOLYMER COMPRISING AT LEAST ONE OF N-OXYGENATEDHYDROCARBONAMIDE MONOMERS AND AT LEAST ONE OF AMINO ACID MONOMERS, POLYSUCCINIMIDES NALCO CHEMICAL COMPANY (US) 1999-01-12 US claimed
US-5776875-A Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-07-07 US claimed
EP-0831066-A1 Biodegradable Aspartic acid polymers for preventing scale formation in boilers NALCO CHEMICAL COMPANY (US) 1998-03-25 EP claimed
EP-0819653-A2 Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-01-21 EP claimed
US-5858244-A COPOLYMER COMPRISING AT LEAST ONE OF N-OXYGENATEDHYDROCARBONAMIDE MONOMERS AND AT LEAST ONE OF AMINO ACID MONOMERS, POLYSUCCINIMIDES NALCO CHEMICAL COMPANY (US) 1999-01-12 US disclosed
US-5776875-A Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-07-07 US disclosed
EP-0819653-A2 Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-01-21 EP disclosed