Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 10/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 6/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL865129 | 0.85 | HSD11B1 (0.58) | ALDH1A1HPGDSMN1; SMN2HSD11B1EPHX2 | |
| SCHEMBL16242079 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HPGDSMN1; SMN2HSD11B1EPHX2 | |
| SCHEMBL16242078 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2HSD11B1EPHX2 | |
| SCHEMBL18193472 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2HSD11B1EPHX2 | |
| SCHEMBL21015325 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2HSD11B1EPHX2 | |
| SCHEMBL7048462 | 0.79 | KMT2A (0.59) | ALDH1A1HPGDSMN1; SMN2IDO1AGXT | |
| SCHEMBL3818379 | 0.79 | LOXL2 (0.55) | ALDH1A1HPGDSMN1; SMN2HSD11B1EPHX2 | |
| SCHEMBL14101266 | 0.77 | HSD11B1 (0.52) | ALDH1A1HPGDSMN1; SMN2HSD11B1EPHX2 | |
| Hydrochloric Acid SCHEMBL9726409 | 0.77 | LOXL2 (0.53) | ALDH1A1HPGDSMN1; SMN2HSD11B1EPHX2 | |
| SCHEMBL7153089 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2HSD11B1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |