Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745921 | 0.84 | MEN1 (0.41) | MEN1KMT2AUSP2L3MBTL1CYP3A4 | |
| SCHEMBL7746911 | 0.83 | MEN1 (0.45) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL7745691 | 0.80 | SMN1; SMN2 (0.47) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL7741901 | 0.79 | POLB (0.44) | MEN1KMT2AUSP2L3MBTL1CYP3A4 | |
| SCHEMBL7747488 | 0.78 | SMN1; SMN2 (0.40) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL7746351 | 0.72 | FEN1 (0.44) | MEN1KMT2ACYP3A4SMN1; SMN2POLB | |
| SCHEMBL7746317 | 0.71 | MEN1 (0.43) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL7746045 | 0.70 | SMN1; SMN2 (0.64) | MEN1KMT2ASMN1; SMN2CXCR4POLB | |
| SCHEMBL7741401 | 0.70 | MEN1 (0.59) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL7745852 | 0.70 | CYP3A4 (0.59) | MEN1KMT2AUSP2L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |