Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28610041 | 0.70 | — | — | |
| SCHEMBL62942 | 0.69 | KDM4E (0.59) | MEN1KMT2AMAPTGAAKDM4E | |
| Benzene SCHEMBL27623238 | 0.69 | KDM4E (0.59) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL14096313 | 0.69 | CTSG (0.45) | MAPTGAAKDM4ETDP1MMP3 | |
| SCHEMBL8473466 | 0.66 | ALOX12 (0.41) | MEN1KMT2AALDH1A1ALOX12NPC1 | |
| SCHEMBL10649531 | 0.66 | EPHX2 (0.62) | MEN1KMT2AGAADDB1CRBN | |
| SCHEMBL11060522 | 0.66 | GAA (0.39) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL5954446 | 0.64 | ALDH1A1 (0.63) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL123633 | 0.63 | GRK5 (0.56) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL28453752 | 0.62 | LTA4H (0.44) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066785-A | CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING | CITY OF HOPE (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0407527-A4 | CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING | — | 1991-10-30 | — | — | EP | disclosed |
| EP-0407527-A1 | CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING | CITY OF HOPE (US) | 1991-01-16 | — | — | EP | disclosed |
| US-4935494-A | C-terminal peptide and protein sequencing | CITY OF HOPE (US) | 1990-06-19 | — | — | US | disclosed |
| WO-1990005739-A1 | CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING | MILLER CHAD G (US) | 1990-05-31 | — | — | WO | disclosed |