Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP4 | Q02790 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 3/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667052 | 0.95 | FKBP4 (0.58) | FKBP4TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL7076149 | 0.94 | FKBP4 (0.56) | FKBP4TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL11103910 | 0.92 | FKBP4 (0.58) | FKBP4TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL6058133 | 0.90 | OPRM1 (0.56) | FKBP4TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL7746384 | 0.90 | KMT2A (0.58) | FKBP4TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL410223 | 0.90 | FKBP4 (0.54) | FKBP4TACR1USP30 | |
| SCHEMBL10305897 | 0.90 | FKBP4 (0.70) | FKBP4TACR1USP30 | |
| SCHEMBL29361508 | 0.90 | FKBP4 (0.70) | FKBP4TACR1USP30 | |
| SCHEMBL1295326 | 0.89 | F2 (0.54) | FKBP4TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL27843840 | 0.89 | F2 (0.54) | FKBP4TACR1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220921-A2 | Heat stable alkaline proteases produced by a bacillus | GENEX CORPORATION (US) | 1987-05-06 | — | — | EP | claimed |
| US-20260132396-A1 | PERFORMANCE-ENHANCED PROTEASE VARIANTS | HENKEL AG & CO KGAA (DE) | 2026-05-14 | — | — | US | disclosed |
| US-12606811-B2 | Cleaning performance on protein sensitive soilings VI | HENKEL AG & CO. KGAA (DE) | 2026-04-21 | — | — | US | disclosed |
| EP-4705447-A1 | PERFORMANCE-ENHANCED PROTEASE VARIANTS | Henkel AG & Co. KGaA (DE) | 2026-03-11 | — | — | EP | disclosed |
| US-20260043015-A1 | PERFORMANCE-ENHANCED PROTEASE VARIANTS X | HENKEL AG & CO KGAA (DE) | 2026-02-12 | — | — | US | disclosed |
| US-20260028609-A1 | PROTEASE VARIANTS WITH IMPROVED STORAGE STABILITY | HENKEL AG & CO KGAA (DE) | 2026-01-29 | — | — | US | disclosed |
| US-12492360-B2 | Highly alkaline textile washing agent comprising protease | HENKEL AG & CO. KGAA (DE) | 2025-12-09 | — | — | US | disclosed |
| EP-4649127-A1 | ENZYME-CONTAINING DETERGENTS AND CLEANING AGENTS | Henkel AG & Co. KGaA (DE) | 2025-11-19 | — | — | EP | disclosed |
| EP-4634353-A1 | DETERGENTS AND CLEANING AGENTS CONTAINING PROTEASE | Henkel AG & Co. KGaA (DE) | 2025-10-22 | — | — | EP | disclosed |
| EP-4634354-A1 | DETERGENTS AND CLEANING AGENTS CONTAINING PROTEASE | Henkel AG & Co. KGaA (DE) | 2025-10-22 | — | — | EP | disclosed |
| WO-1995010592-A1 | BLEACHING COMPOSITIONS COMPRISING PROTEASE ENZYMES | THE PROCTER & GAMBLE COMPANY (US) | 1995-04-20 | — | — | WO | disclosed |
| WO-1994023053-A1 | PROTEASE VARIANTS | NOVO NORDISK A/S (DK) | 1994-10-13 | — | — | WO | disclosed |
| US-5316935-A | Subtilisin variants suitable for hydrolysis and synthesis in organic media | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1994-05-31 | — | — | US | disclosed |
| EP-0409878-A4 | SUBTILISIN MUTATIONS | — | 1991-06-19 | — | — | EP | disclosed |
| EP-0409878-A1 | SUBTILISIN MUTATIONS | Enzon Labs Inc. (US) | 1991-01-30 | — | — | EP | disclosed |
| WO-1990014420-A1 | MULTIPLY MUTATED SUBTILISINS | AMGEN INC. (US) | 1990-11-29 | — | — | WO | disclosed |
| EP-0398539-A1 | Multiply mutated subtilisins | AMGEN INC. (US) | 1990-11-22 | — | — | EP | disclosed |
| WO-1989009830-A1 | SUBTILISIN MUTATIONS | GENEX CORPORATION (US) | 1989-10-19 | — | — | WO | disclosed |
| EP-0169114-A2 | Human alpha-1-antitrypin derivatives and process for their preparation | TRANSGENE S.A. (FR) | 1986-01-22 | — | — | EP | disclosed |
| WO-1986000337-A1 | HUMAN alpha1-ANTITRYPSIN DERIVATIVES AND PREPARATION PROCESS THEREOF | TRANSGENE S.A. (FR) | 1986-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260043015-A1 | PERFORMANCE-ENHANCED PROTEASE VARIANTS X | CTRL, PRSS1, XPNPEP1 | FKBP4 2672/4885TACR1 2185/4885OPRM1 3515/4885 |
| US-12606811-B2 | Cleaning performance on protein sensitive soilings VI | CTRL, SENP3, UCHL1 | FKBP4 4676/4885TACR1 4352/4885OPRM1 4606/4885 |
| US-20260132396-A1 | PERFORMANCE-ENHANCED PROTEASE VARIANTS | CTRL, DPEP1, MME | FKBP4 4160/4885TACR1 2971/4885OPRM1 4096/4885 |
| US-20260028609-A1 | PROTEASE VARIANTS WITH IMPROVED STORAGE STABILITY | UBE2V1, CTRL, UCHL1 | FKBP4 2673/4885TACR1 4094/4885OPRM1 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.