Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986402 | 0.83 | NAAA (0.61) | NAAALMNAPAX8TSHRHTT | |
| SCHEMBL6436285 | 0.82 | CNR1 (0.69) | NAAALMNAPAX8CNR1CNR2 | |
| SCHEMBL7350719 | 0.81 | NAAA (0.72) | NAAALMNAPAX8HTTMEN1 | |
| SCHEMBL8507424 | 0.81 | NAAA (0.72) | NAAALMNAPAX8HTTMEN1 | |
| SCHEMBL14861138 | 0.79 | POLB (0.61) | KDM4ACNR1CNR2KMT2APOLB | |
| SCHEMBL4985814 | 0.78 | NAAA (0.68) | NAAALMNAPAX8HTTKDM4A | |
| SCHEMBL2843459 | 0.78 | NAAA (0.68) | NAAALMNAPAX8HTTKDM4A | |
| SCHEMBL4243720 | 0.78 | KMT2A (0.49) | LMNAMEN1KMT2AHPGDPOLB | |
| SCHEMBL6446787 | 0.78 | CTSS (0.52) | — | |
| SCHEMBL2334318 | 0.78 | NAAA (0.72) | NAAALMNAPAX8CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001010798-A1 | SOLID PHASE SYNTHESIS OF OXA- AND THIAZOLES | CHEMRX ADVANCED TECHNOLOGIES, INC. (US) | 2001-02-15 | — | — | WO | disclosed |