SCHEMBL774702

SCHEMBL774702

O=[N+]([O-])c1ccc2c(O)cccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 4/20 0.52
▸ ALDH1A1 P00352 2/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ GPR35 Q9HC97 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ PLAU P00749 1/20 0.50
▸ LMNA P02545 1/20 0.50
▸ TP53 P04637 1/20 0.50
▸ HPGD P15428 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ S100A4 P26447 1/20 0.49
▸ GAA P10253 1/20 0.49
▸ THRB P10828 1/20 0.49
▸ KDM4E B2RXH2 1/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ PKM P14618 1/20 0.47
▸ NFKB1 P19838 1/20 0.47
▸ HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Nitrophenol SCHEMBL5573898 0.94 ESR1 (0.54) TSHRALDH1A1ALOX15GPR35TDP1
SCHEMBL4958995 0.86 TSHR (0.52) TSHRALDH1A1ALOX15GPR35SMN1; SMN2
Dinitrophenylene SCHEMBL27352655 0.84 LMNA (0.59) TSHRALDH1A1ALOX15TDP1SMN1; SMN2
SCHEMBL28257786 0.81 TSHR (0.54) TSHRALDH1A1ALOX15TDP1LMNA
SCHEMBL4960980 0.80 TDP1 (0.66) TSHRALDH1A1ALOX15GPR35TDP1
SCHEMBL8668528 0.80 TSHR (0.66) TSHRALDH1A1GPR35TDP1SMN1; SMN2
SCHEMBL774010 0.79 CASP6 (0.58) TSHRALDH1A1ALOX15GPR35TDP1
SCHEMBL14375281 0.79 HSD17B10 (0.53) TSHRALDH1A1TDP1LMNAGAA
SCHEMBL5172969 0.79 ALDH1A1 (0.55) TSHRALDH1A1ALOX15GPR35TDP1
SCHEMBL8686354 0.79 TDP1 (0.52) TSHRALDH1A1ALOX15TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3842076-B1 MULTI-LAYER WOUND CARE PRODUCT WITH PERFORATED RELEASE LAYER BSN MEDICAL GMBH (DE) 2023-02-15 — — EP claimed
EP-3558399-B1 MULTI-LAYER WOUND CARE PRODUCT WITH PERFORATED RELEASE LAYER BSN MEDICAL GMBH (DE) 2021-01-20 — — EP claimed
EP-3338813-B1 MULTI-LAYER WOUND CARE PRODUCT WITH PERFORATED RELEASE LAYER BSN MEDICAL GMBH (DE) 2020-01-29 — — EP claimed
EP-3318532-A1 METHOD AND DEVICE FOR NO INSTILLATION BSN medical GmbH (DE) 2018-05-09 — — EP claimed
EP-3288893-A1 MULTI-STEP PROCESS FOR NO PRODUCTION BSN Medical Holding GmbH (DE) 2018-03-07 — — EP claimed
WO-2016174043-A1 MULTI-STEP PROCESS FOR NO PRODUCTION BSN MEDICAL GMBH (DE) 2016-11-03 — — WO claimed
US-7211414-B2 Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity VISIGEN BIOTECHNOLOGIES, INC. (US) 2007-05-01 — — US claimed
EP-3415641-B1 METHOD FOR ANALYSIS OF MOLECULES PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2023-11-01 — — EP disclosed
EP-3534809-B1 DEBRIDEMENT DEVICE BSN MEDICAL GMBH (DE) 2020-09-02 — — EP disclosed
EP-3458115-B1 WOUND OR SKIN PATCH BSN MEDICAL GMBH (DE) 2020-08-26 — — EP disclosed
EP-3534809-A1 DEBRIDEMENT DEVICE BSN Medical GmbH (DE) 2019-09-11 — — EP disclosed
EP-3288517-B1 MEDICAL BATHING DEVICE BSN MEDICAL GMBH (DE) 2019-07-17 — — EP disclosed
EP-3458115-A1 WOUND DRESSING OR DERMAL PATCH BSN Medical GmbH (DE) 2019-03-27 — — EP disclosed
US-20060061755-A1 Apparatus and method for analysis of molecules PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2006-03-23 — — US disclosed
US-20060061754-A1 Arrays of optical confinements and uses thereof PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2006-03-23 — — US disclosed
WO-2004041840-A2 PEPTIDE-BOUND CHROMOGENS USED FOR DETERMINING ENZYMATIC ACTIVITIES C-CIT AG (CH) 2004-05-21 — — WO disclosed
EP-1354064-A2 ENZYMATIC NUCLEIC ACID SYNTHESIS: COMPOSITIONS AND METHODS FOR ALTERING MONOMER INCORPORATION FIDELITY Visigen Biotechnologies, Inc. (US) 2003-10-22 — — EP disclosed
US-20030134807-A1 Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity Life Technologies Corporation 2003-07-17 — — US disclosed
WO-2002044425-A2 ENZYMATIC NUCLEIC ACID SYNTHESIS: COMPOSITIONS AND METHODS FOR ALTERING MONOMER INCORPORATION FIDELITY VISIGEN BIOTECHNOLOGIES, INC. (US) 2002-06-06 — — WO disclosed
US-6399335-B1 MIXING POLYMERASE AND NUCLEOSIDE TRIPHOSPHATE HAVING A GAMMA PHOSPHATE PHOSPHOESTER-LINKED FUNCTIONAL GROUP, INCUBATING SO THAT POLYMERASE CATALYZES CLEAVAGE BETWEEN ALPHA AND BETA PHOSPHATES AND LIBERATES PYROPHOSPHATE WITH FUNCTIONAL GROUP ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. 2002-06-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030134807-A1 Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity RNGTT, PNP, MTAP TSHR 4361/4885ALDH1A1 1522/4885ALOX15 3324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback