Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Trichloroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichloroacetic Acid SCHEMBL9784169 | 0.92 | ALDH1A1 (0.47) | — | |
| Trichloroacetic Acid SCHEMBL19810503 | 0.92 | ALDH1A1 (0.47) | — | |
| Trichloroacetic Acid SCHEMBL11108028 | 0.92 | ALDH1A1 (0.47) | — | |
| Trichloroacetic Acid SCHEMBL7787579 | 0.92 | — | — | |
| Trichloroacetic Acid SCHEMBL465138 | 0.92 | ALDH1A1 (0.47) | — | |
| Trichloroacetic Acid SCHEMBL60578 | 0.92 | — | — | |
| Trichloroacetic Acid SCHEMBL7211445 | 0.92 | ALDH1A1 (0.47) | — | |
| Trichloroacetic Acid SCHEMBL18685945 | 0.92 | ALDH1A1 (0.47) | — | |
| Trichloroacetic Acid SCHEMBL1178275 | 0.92 | ALDH1A1 (0.47) | — | |
| Trichloroacetic Acid SCHEMBL108356 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012303-A1 | CLEAN, HIGH-YIELD PREPARATION OF S,S AND R,S AMINO ACID ISOSTERES | AEROJET FINE CHEMICALS LLC (US) | 2009-01-08 | — | — | US | claimed |
| US-6867311-B2 | Clean, high-yield preparation of S,S and R,S amino acid isosteres | AEROJET FINE CHEMICALS LLC (US) | 2005-03-15 | — | — | US | claimed |
| US-20030225292-A1 | Clean, high-yield preparation of S,S and R,S amino acid isosteres | AEROJET FINE CHEMICALS LLC, A DELAWARE LIMITED LIABILITY COMPANY | 2003-12-04 | — | — | US | claimed |
| US-20030032052-A1 | Methods and apparatus for template capture and normalization for submicroliter reaction | MOLECULAR DYNAMICS, INC. | 2003-02-13 | — | — | US | claimed |
| US-6489112-B1 | PREPARING NANOSCALE REACTIONS USING NUCLEIC ACIDS ARE PRESENTED. NUCLEIC ACIDS ARE CAPTURED SATURABLY, YET REVERSIBLY, ON THE INTERNAL SURFACE OF THE REACTION CHAMBER, TYPICALLY A CAPILLARY. EXCESS NUCLEIC ACID IS REMOVED AND THE | MOLECULAR DYNAMICS, INC. | 2002-12-03 | — | — | US | claimed |
| EP-1203099-A2 | METHODS AND APPARATUS FOR TEMPLATE CAPTURE AND NORMALIZATION FOR SUBMICROLITER REACTION | MOLECULAR DYNAMICS, INC. (US) | 2002-05-08 | — | — | EP | claimed |
| WO-2001009389-A2 | METHODS AND APPARATUS FOR TEMPLATE CAPTURE AND NORMALIZATION FOR SUBMICROLITER REACTION | MOLECULAR DYNAMICS, INC. (US) | 2001-02-08 | — | — | WO | claimed |
| US-5869583-A | BULK, SOLUTION, EMULSION OR SUSPENSION POLYMERIZATION IN PRESENCE OF INITIATING SYSTEM COMPRISING RADICAL GENERATING COMPOUND AND METAL COMPLEX CATALYST CONTAINING SPECIFIED LIGAND | ELF ATOCHEM S.A. (FR) | 1999-02-09 | — | — | US | claimed |
| WO-1992018649-A1 | COMPOSITIONS AND METHODS FOR IMPROVED EXTRACTION AND HYBRIDIZATION OF NUCLEIC ACID | MICROPROBE CORPORATION (US) | 1992-10-29 | — | — | WO | claimed |
| US-H691-H | CONTAINING IMIDOTHIOESTER COMPOUND AND BASE PRECURSOR; HEAT RESISTANCE, STABILITY, ANTIFOGGING AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | claimed |
| JP-59150792-A | — | — | None | — | — | JP | disclosed |
| US-20260118767-A1 | REVERSE PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-04-30 | — | — | US | disclosed |
| US-20260044081-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST FILM AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-02-12 | — | — | US | disclosed |
| EP-4692941-A2 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST FILM AND PATTERNING PROCESS | Shin-Etsu Chemical Co., Ltd. (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-4621486-A2 | POLYVALENT AMMONIUM SALT COMPOUND, COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-09-24 | — | — | EP | disclosed |
| US-4159377-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4054656-A | ASTHMA, HAY FEVER, FOODS | MEAD JOHNSON & COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4014865-A | Golden-yellow fiber-reactive water-soluble monoazo dyestuffs | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |
| US-3975385-A | 7-Trichloroacetamido-3-desacetoxy-cephalosporanic acid esters | RHONE-POULENC S.A. (FR) | 1976-08-17 | — | — | US | disclosed |
| US-3953305-A | OSMIUM TETROXIDE, OXIDATION WITH CHROMIUM | STANDARD OIL COMPANY (US) | 1976-04-27 | — | — | US | disclosed |