Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | IDE | P14735 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747562 | 0.77 | IDE (0.47) | CLK1RXFP1MAPK1IDEALDH1A1 | |
| SCHEMBL15933252 | 0.77 | MAPK1 (0.58) | MAPK1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15933288 | 0.77 | MAPK1 (0.58) | MALT1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL5681145 | 0.77 | MALT1 (0.51) | CLK1MALT1IDEALDH1A1MEN1 | |
| SCHEMBL13210167 | 0.76 | LMNA (0.54) | CLK1RXFP1IDEMEN1KMT2A | |
| SCHEMBL7744802 | 0.76 | CCR5 (0.47) | CLK1RXFP1MAPK1IDEALDH1A1 | |
| SCHEMBL13871101 | 0.75 | NTSR1 (0.47) | CLK1MALT1MAPK1IDEALDH1A1 | |
| SCHEMBL8871837 | 0.75 | RXFP1 (0.58) | CLK1RXFP1MAPK1IDEALDH1A1 | |
| SCHEMBL7747563 | 0.74 | IDE (0.45) | CLK1RXFP1IDEALDH1A1MEN1 | |
| SCHEMBL15933284 | 0.74 | MAPK1 (0.54) | MAPK1ALDH1A1HSD17B10MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002385-A1 | 1-(QUINOLIN-4-YL)-1H-PYRAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-11 | — | — | WO | claimed |