Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747684 | 0.83 | CTSK (0.38) | CTSKCTSSITGB3ITGA2B | |
| SCHEMBL4519161 | 0.78 | CTSK (0.32) | CTSKCTSSITGB3ITGA2B | |
| SCHEMBL10431195 | 0.67 | CA1 (0.45) | CTSKCTSSITGB3ITGA2B | |
| SCHEMBL8525452 | 0.67 | ITGB3 (0.42) | CTSKCTSSITGB3ITGA2B | |
| SCHEMBL25533140 | 0.67 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL15415011 | 0.66 | CA1 (0.42) | CTSKCTSSITGB3ITGA2B | |
| SCHEMBL4382302 | 0.66 | CA1 (0.46) | CTSKCTSSITGB3ITGA2B | |
| SCHEMBL28668062 | 0.66 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL28668065 | 0.66 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL25985137 | 0.66 | CTSK (0.50) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070047-A2 | LIPIDS | Celltech Chiroscience Limited (GB) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052858-A2 | LIPIDS | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-10-21 | — | — | WO | disclosed |