Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.49 |
| ▸ | TACR1 | P25103 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoylphenylurea SCHEMBL83109 | 0.79 | L3MBTL1 (0.48) | MAPTTRPM8CES2L3MBTL1RAB9A | |
| SCHEMBL6437333 | 0.78 | TRPM8 (0.38) | P2RX1TACR1MAPTCNR1CNR2 | |
| SCHEMBL7753462 | 0.78 | TRPM8 (0.38) | P2RX1TACR1MAPTCNR1CNR2 | |
| SCHEMBL29866000 | 0.78 | TRPM8 (0.38) | P2RX1TACR1MAPTCNR1CNR2 | |
| Benzoylphenylurea SCHEMBL31707309 | 0.78 | TDP1 (0.46) | MAPTTRPM8CES2L3MBTL1NPC1 | |
| SCHEMBL31188158 | 0.78 | TACR1 (0.49) | P2RX1TACR1MAPTCNR1CNR2 | |
| SCHEMBL27659224 | 0.76 | KMT2A (0.49) | MAPTTRPM8L3MBTL1NPC1RAB9A | |
| SCHEMBL7754437 | 0.75 | POLB (0.39) | MAPTTRPM8L3MBTL1NR1H2NR1H3 | |
| SCHEMBL28020267 | 0.74 | CES2 (0.51) | MAPTCNR2TRPM8CES2RAB9A | |
| SCHEMBL6037561 | 0.72 | CES2 (0.48) | MAPTTRPM8AKR1C3CES2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912502-B1 | 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2001-01-17 | — | — | EP | disclosed |
| US-6022882-A | POTENT GROWTH-RETARDING ACTIVITY AGAINST PESTS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2000-02-08 | — | — | US | disclosed |
| EP-0912502-A1 | 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME | Hanwha Corporation (KR) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000394-A1 | 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME | HANWHA CORPORATION (KR) | 1998-01-08 | — | — | WO | disclosed |