SCHEMBL7754437

SCHEMBL7754437

NC(=O)N(C(=O)c1ccccc1)c1ccccc1C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.39
MRGPRX4 Q96LA9 1/20 0.38
CES1 P23141 1/20 0.38
MAPT P10636 2/20 0.37
CYP3A4 P08684 1/20 0.37
PARP1 P09874 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KCNK3 O14649 1/20 0.37
KCNK9 Q9NPC2 1/20 0.37
MAOB P27338 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10672986 0.81 POLB (0.44) POLBCES1MAPTKCNK3KCNK9
SCHEMBL11092653 0.81 LMNA (0.38) POLBTDP1L3MBTL1MAOBLMNA
SCHEMBL29866000 0.78 TRPM8 (0.38) POLBMRGPRX4MAPTTRPM8LMNA
SCHEMBL7753462 0.78 TRPM8 (0.38) MAPTTRPM8LMNAHDAC6POLQ
SCHEMBL6437333 0.78 TRPM8 (0.38) POLBMRGPRX4MAPTTRPM8LMNA
SCHEMBL5331837 0.76 LMNA (0.42) POLBTDP1L3MBTL1MAOBLMNA
SCHEMBL2913048 0.76 L3MBTL1 (0.41) POLBCES1MAPTCYP3A4PARP1
SCHEMBL27659219 0.76 TSHR (0.41) POLBCES1MAPTCYP3A4PARP1
SCHEMBL7748811 0.75 P2RX1 (0.49) MAPTL3MBTL1TRPM8LMNANR1H2
SCHEMBL194877 0.75 LMNA (0.41) POLBTDP1L3MBTL1MAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0912502-B1 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME DONGBU HANNONG CHEMICAL CO LTD (KR) 2001-01-17 EP claimed
US-6022882-A POTENT GROWTH-RETARDING ACTIVITY AGAINST PESTS DONGBU HANNONG CHEMICAL CO., LTD. (KR) 2000-02-08 US claimed
EP-0912502-A1 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME Hanwha Corporation (KR) 1999-05-06 EP claimed
WO-1998000394-A1 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME HANWHA CORPORATION (KR) 1998-01-08 WO claimed
CN-107041377-A A kind of Pesticidal combination containing double third ring worm esters and bistrifluron 佛山市盈辉作物科学有限公司 2017-08-15 CN disclosed