Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 3/20 | 0.39 |
| ▸ | METAP1 | P53582 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749016 | 0.82 | EDNRA (0.39) | CBFBHPGDSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL10466047 | 0.73 | L3MBTL1 (0.67) | SMN1; SMN2ALDH1A1TP53CYP3A4HSD17B10 | |
| SCHEMBL6738508 | 0.72 | STK33 (0.54) | CBFBHPGDSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL23105410 | 0.72 | CBFB (0.50) | CBFBHPGDSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL13504643 | 0.70 | CBFB (0.57) | CBFBHPGDSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL2872550 | 0.70 | CBFB (0.50) | CBFBHPGDSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL10466134 | 0.70 | PKN1 (0.50) | SMN1; SMN2ALDH1A1CYP3A4CYP2D6ALOX15 | |
| SCHEMBL10429390 | 0.69 | CBFB (0.46) | CBFBHPGDSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8062130 | 0.69 | CBFB (0.49) | CBFBHPGDSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL6638459 | 0.68 | EDNRA (0.42) | SMN1; SMN2ALDH1A1METAP1IDO1EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001022985-A1 | USE OF PENTAGASTRIN TO INHIBIT GASTRIC ACID SECRETION OR AS A DIURETIC | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-04-05 | — | — | WO | disclosed |