Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749014 | 0.82 | CBFB (0.44) | EDNRALMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4313385 | 0.76 | NPC1 (0.45) | LMNANPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL27837532 | 0.74 | METAP2 (0.63) | LMNANPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL10466047 | 0.72 | L3MBTL1 (0.67) | LMNANPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL6738508 | 0.72 | STK33 (0.54) | LMNANPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL31402009 | 0.71 | L3MBTL1 (0.60) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL13504644 | 0.71 | NPC1 (0.50) | LMNANPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL1989677 | 0.70 | NPC1 (0.40) | LMNANPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL10922585 | 0.69 | TGFBR1 (0.46) | EDNRANPC1RAB9ASMN1; SMN2METAP2 | |
| SCHEMBL6675102 | 0.68 | L3MBTL1 (0.55) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001022985-A1 | USE OF PENTAGASTRIN TO INHIBIT GASTRIC ACID SECRETION OR AS A DIURETIC | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-04-05 | — | — | WO | disclosed |