Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK33 | Q9BYT3 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27214319 | 0.80 | SLC40A1 (0.62) | LMNAMETAP2METAP1ALDH1A1MEN1 | |
| SCHEMBL30925465 | 0.80 | SLC40A1 (0.62) | LMNAMETAP2METAP1ALDH1A1MEN1 | |
| SCHEMBL10467765 | 0.79 | ALDH1A1 (0.56) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL10466744 | 0.76 | RECQL (0.54) | STK33HPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL28408197 | 0.76 | SLC40A1 (0.56) | STK33SMN1; SMN2LMNAMETAP2METAP1 | |
| SCHEMBL7749014 | 0.72 | CBFB (0.44) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL1206957 | 0.72 | KDM1A (0.54) | NPC1RAB9AL3MBTL1CDK1CDK2 | |
| SCHEMBL477759 | 0.72 | L3MBTL1 (0.53) | STK33NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7749016 | 0.72 | EDNRA (0.39) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL5324494 | 0.71 | ALDH1A1 (0.70) | NPC1HPGDSMN1; SMN2LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004098609-A1 | BENZOTRIAZEPINE DERIVATIVES AND THEIR USE AS GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2004-11-18 | — | — | WO | disclosed |