SCHEMBL7749191

SCHEMBL7749191

C=C(OCCOc1ccc(Br)c(Br)c1Br)C(=O)OCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 5/20 0.35
LMNA P02545 4/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
NPSR1 Q6W5P4 2/20 0.35
S1PR4 O95977 1/20 0.35
S1PR1 P21453 1/20 0.35
MAPK1 P28482 1/20 0.35
FDPS P14324 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
L3MBTL1 Q9Y468 4/20 0.34
TDP1 Q9NUW8 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
GAA P10253 2/20 0.33
PRNP P04156 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15226845 0.83 MAPT (0.39) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL5704184 0.82 THRB (0.42) ALDH1A1KDM4ELMNANPC1RAB9A
SCHEMBL7692625 0.81 LMNA (0.38) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL10885708 0.74 THRB (0.53) ALDH1A1KDM4EKMT2AFDPSNPC1
SCHEMBL94045 0.73 TDP1 (0.37) MAPTALDH1A1KDM4ELMNAS1PR4
SCHEMBL8675831 0.73 ALDH1A1 (0.35) MAPTALDH1A1KDM4ELMNAMEN1
SCHEMBL2383703 0.73 THRB (0.54) MAPTALDH1A1KDM4ELMNAMEN1
SCHEMBL28452219 0.72 KDM4E (0.51) ALDH1A1KDM4ELMNAMEN1KMT2A
SCHEMBL7749061 0.71 ALDH1A1 (0.53) ALDH1A1KDM4ELMNAKMT2ANPC1
SCHEMBL11398711 0.70 HPGD (0.44) MAPTALDH1A1KDM4ELMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6218074-B1 BLEND OF BROMOPOLYMER AND OTHER ADDITION POLYMER E. I. DU PONT DE NEMOURS AND COMPANY 2001-04-17 US claimed