Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11163982 | 0.83 | TSHR (0.37) | ALDH1A1MAPTLMNAKMT2ARAB9A | |
| SCHEMBL7692625 | 0.79 | LMNA (0.38) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL15226845 | 0.75 | MAPT (0.39) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL7749191 | 0.73 | MAPT (0.35) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL5607039 | 0.72 | THRB (0.38) | ALDH1A1MAPK1SMN1; SMN2TSHR | |
| SCHEMBL7692628 | 0.72 | CA12 (0.37) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL6660310 | 0.70 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL1153546 | 0.70 | MAPT (0.41) | ALDH1A1MAPTLMNAKMT2ARAB9A | |
| SCHEMBL94679 | 0.69 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL10712256 | 0.67 | GABRA1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741831-A | Polymerizable compositions based on thio (meth) acrylate monomers, polymers with a low yellow index obtained from such compositions, and corresponding ophthalmic lenses | ESSILOR INTERNATIONAL - COMPAGNIE GENERALE D'OPTIQUE (FR) | 1998-04-21 | — | — | US | disclosed |