SCHEMBL7750490

SCHEMBL7750490

Cc1ccc(Cc2ccccc2S(=O)(=O)c2ccccc2Cc2ccc(C)cc2C)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.39
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
GFER P55789 1/20 0.39
NR3C1 P04150 1/20 0.38
PGR P06401 1/20 0.38
NR3C2 P08235 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38
HSD11B1 P28845 1/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
RAPGEF4 Q8WZA2 2/20 0.36
TNF P01375 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7749407 0.84 PTGDR2 (0.44) ALDH1A1PTGDR2KMT2AMEN1KDM4E
SCHEMBL6546220 0.80 RAB9A (0.44) RAB9AHTTSMN1; SMN2LMNANPC1
SCHEMBL11323610 0.80 TAAR1 (0.43) RAB9AHTTSMN1; SMN2LMNANPC1
SCHEMBL3299248 0.78 PYCR1 (0.47) RAB9AHTTSMN1; SMN2LMNANPC1
SCHEMBL9820069 0.77 MEN1 (0.42) POLBPTGDR2KMT2AMEN1
SCHEMBL8367825 0.77 AMY1A (0.37) RAB9AHTTSMN1; SMN2NPC1ALDH1A1
SCHEMBL29155377 0.74 PYCR1 (0.40) RAB9AHTTSMN1; SMN2LMNANPC1
SCHEMBL11194149 0.74 LMNA (0.48) RAB9AHTTSMN1; SMN2LMNANPC1
SCHEMBL21323294 0.74 HTT (0.46) RAB9AHTTSMN1; SMN2LMNANPC1
SCHEMBL7460688 0.74 HSPA5 (0.59) RAB9AHTTSMN1; SMN2NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001029837-A1 MEDIUM FOR FLUORESCENT READ-ONLY MULTILAYER OPTICAL INFORMATION CARRIER AND ITS MANUFACTURING METHOD TRID STORE IP, LLC (US) 2001-04-26 WO claimed
WO-2001029837-A1 MEDIUM FOR FLUORESCENT READ-ONLY MULTILAYER OPTICAL INFORMATION CARRIER AND ITS MANUFACTURING METHOD TRID STORE IP, LLC (US) 2001-04-26 WO disclosed
US-5885745-A PHOTOLITHOGRAPHIC DIELECTRIC FILM HITACHI CHEMICAL CO., LTD. (JP) 1999-03-23 US disclosed