Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13259833 | 0.91 | CYP2C19 (0.53) | CYP2C19CYP1A2CYP2C9CYP2D6ALOX5 | |
| SCHEMBL2001926 | 0.89 | ALOX5 (0.46) | CYP2C19CYP1A2CYP2C9CYP2D6ALOX5 | |
| SCHEMBL5464370 | 0.84 | ALDH1A1 (0.45) | CYP2C19CYP1A2CYP2C9CYP2D6GAA | |
| SCHEMBL14702161 | 0.83 | CYP2C19 (0.46) | CYP2C19CYP1A2CYP2C9CYP2D6ALOX5 | |
| SCHEMBL12118510 | 0.80 | MEN1 (0.47) | CYP2C19ALOX5PTGS1GAAGABRA1 | |
| SCHEMBL331989 | 0.79 | GAA (0.53) | ALOX5PTGS1PTGS2GAAGABRA1 | |
| SCHEMBL240977 | 0.79 | ALOX15 (0.53) | CYP2C19ALOX5PTGS1PTGS2GAA | |
| SCHEMBL14283804 | 0.79 | ALOX5 (0.49) | ALOX5PTGS1PTGS2GAAGABRA1 | |
| SCHEMBL70807 | 0.79 | CYP2C19 (0.53) | CYP2C19CYP1A2CYP2C9CYP2D6HTR1D | |
| SCHEMBL22588951 | 0.79 | ALOX5 (0.41) | CYP2C19CYP1A2CYP2C9CYP2D6ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249106-B2 | Substituted hydrazide compounds and use thereof | SHENYANG J & HEALTH PHARMACEUTICAL CO., LTD. (CN) | 2016-02-02 | — | — | US | disclosed |
| US-9249106-B2 | Substituted hydrazide compounds and use thereof | SHENYANG J & HEALTH PHARMACEUTICAL CO., LTD. (CN) | 2016-02-02 | — | — | US | disclosed |
| EP-2468730-A1 | SUBSTITUTED HYDRAZIDE COMPOUNDS AND APPLICATION THEREOF | Shenyang J & Health Pharmaceutical Co., Ltd. (CN) | 2012-06-27 | — | — | EP | disclosed |
| US-20120142921-A1 | SUBSTITUTED HYDRAZIDE COMPOUNDS AND USE THEREOF | SHENYANG J & HEALTH PHARMACEUTICAL CO., LTD. (CN) | 2012-06-07 | — | — | US | disclosed |
| US-20120142921-A1 | SUBSTITUTED HYDRAZIDE COMPOUNDS AND USE THEREOF | SHENYANG J & HEALTH PHARMACEUTICAL CO., LTD. (CN) | 2012-06-07 | — | — | US | disclosed |
| US-6306979-B1 | Derivatized carbon monoxide copolymers | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-23 | — | — | US | disclosed |
| US-6284868-B1 | AT LEAST ONE 1-ALKENE THAT IS AN ARYL DERIVATIVE SUBSTITUTED WITH AT LEAST ONE TERMINAL ALLYL AND/OR HOMOALLYL MOIETY AND CONTAINING ONE OR MORE POLAR GROUPS; GROUP VIII METAL COMPLEX CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-04 | — | — | US | disclosed |
| EP-1064317-A1 | DERIVATIZED CARBON MONOXIDE COPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-03 | — | — | EP | disclosed |
| EP-0991696-A1 | FUNCTIONALISED CARBON MONOXIDE COPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999058607-A1 | POLYMER MIXTURES CONTAINING CARBON MONOXIDE/α-OLEFIN COPOLYMERS AND COPOLYMERS MADE OF VINYL AROMATIC COMPOUNDS AND VINYL CYANIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-18 | — | — | WO | disclosed |
| WO-1999047583-A1 | DERIVATIZED CARBON MONOXIDE COPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999000443-A1 | FUNCTIONALISED CARBON MONOXIDE COPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142921-A1 | SUBSTITUTED HYDRAZIDE COMPOUNDS AND USE THEREOF | SLC5A1, VHL, AKR1A1 | CYP2C19 103/4885CYP1A2 132/4885CYP2C9 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.