SCHEMBL240977

SCHEMBL240977

C=CCc1cc(C(C)(C)c2cc(CC=C)c(O)c(CC=C)c2)cc(CC=C)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.53
MAPK1 P28482 1/20 0.53
HTT P42858 1/20 0.53
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
RECQL P46063 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
KDM4E B2RXH2 1/20 0.41
KLF10 Q13118 1/20 0.40
CYP2C19 P33261 1/20 0.40
GAA P10253 1/20 0.39
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2001926 0.91 ALOX5 (0.46) ALOX15MAPK1HTTALDH1A1CYP3A4
SCHEMBL15815111 0.88 KLF10 (0.56) ALOX15MAPK1HTTALDH1A1HPGD
SCHEMBL13259833 0.88 CYP2C19 (0.53) ALOX15MAPK1HTTTSHRHIF1A
SCHEMBL10463863 0.84 ALOX15 (0.39) ALOX15MAPK1HTTALDH1A1CYP3A4
SCHEMBL14702161 0.80 CYP2C19 (0.46) ALOX15MAPK1HTTTSHRHIF1A
SCHEMBL7751691 0.79 CYP2C19 (0.47) HIF1AGABRA1GABRB2KDM4ECYP2C19
SCHEMBL29364812 0.79 KLF10 (0.62) ALOX15HTTALDH1A1HPGDALOX12
SCHEMBL122346 0.79 KLF10 (0.62) ALOX15HTTALDH1A1HPGDALOX12
SCHEMBL29395400 0.79 KLF10 (0.62) ALOX15HTTALDH1A1HPGDALOX12
SCHEMBL241384 0.78 CYP3A4 (0.46) ALOX15MAPK1HTTALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0204659-B1 POLYEPOXYDES AND THEIR USE CIBA-GEIGY AG (CH) 1991-11-21 EP claimed
US-4677170-A Polyepoxides and the use thereof CIBA-GEIGY CORPORATON (US) 1987-06-30 US claimed
EP-0204659-A2 Polyepoxydes and their use CIBA-GEIGY AG (CH) 1986-12-10 EP claimed
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US claimed
WO-2020116646-A1 ORGANIC-INORGANIC COMPOSITE MATERIAL 帝人株式会社 2020-06-11 WO disclosed
US-10428176-B2 Thermosetting alkoxysilyl compound having two or more alkoxysilyl groups, composition and cured product comprising same, use thereof, and method for preparing alkoxysilyl compound KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2019-10-01 US disclosed
US-10428176-B2 Thermosetting alkoxysilyl compound having two or more alkoxysilyl groups, composition and cured product comprising same, use thereof, and method for preparing alkoxysilyl compound KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2019-10-01 US disclosed
US-20180155370-A1 THERMOSETTING ALKOXYSILYL COMPOUND HAVING TWO OR MORE ALKOXYSILYL GROUPS, COMPOSITION AND CURED PRODUCT COMPRISING SAME, USE THEREOF, AND METHOD FOR PREPARING ALKOXYSILYL COMPOUND KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-06-07 US disclosed
US-20180155370-A1 THERMOSETTING ALKOXYSILYL COMPOUND HAVING TWO OR MORE ALKOXYSILYL GROUPS, COMPOSITION AND CURED PRODUCT COMPRISING SAME, USE THEREOF, AND METHOD FOR PREPARING ALKOXYSILYL COMPOUND KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-06-07 US disclosed
US-20180155370-A1 THERMOSETTING ALKOXYSILYL COMPOUND HAVING TWO OR MORE ALKOXYSILYL GROUPS, COMPOSITION AND CURED PRODUCT COMPRISING SAME, USE THEREOF, AND METHOD FOR PREPARING ALKOXYSILYL COMPOUND KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-06-07 US disclosed
US-9896535-B2 Epoxy compound having alkoxysilyl group, method of preparing the same, composition and cured product comprising the same, and uses thereof KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-02-20 US disclosed
US-9896535-B2 Epoxy compound having alkoxysilyl group, method of preparing the same, composition and cured product comprising the same, and uses thereof KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-02-20 US disclosed
EP-0069069-A2 Polymerisable compositions and polymerisation products resulting therefrom CIBA-GEIGY AG (CH) 1983-01-05 EP disclosed
US-4308367-A COATINGS, PRINTING PLATES, PRINTED CIRCUITS CIBA-GEIGY CORPORATION (US) 1981-12-29 US disclosed
EP-0038300-A1 Polymerisable composition and (meth)acrylic ester CIBA-GEIGY AG (CH) 1981-10-21 EP disclosed
EP-0031305-A2 Compositions containing acrylate and their polymerisation CIBA-GEIGY AG (CH) 1981-07-01 EP disclosed
US-4220513-A FOR PRINTED CIRCUITS, COATINGS, PRINTING PLATES, ADHESIVES CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
US-4131707-A POLYMALEIMIDES CIBA-GEIGY CORPORATION (US) 1978-12-26 US disclosed
US-4127615-A POLYIMIDE, ALKENYLPHENOL OR ETHER CIBA-GEIGY CORPORATION (US) 1978-11-28 US disclosed
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10428176-B2 Thermosetting alkoxysilyl compound having two or more alkoxysilyl groups, composition and cured product comprising same, use thereof, and method for preparing alkoxysilyl compound PIEZO1, FTO, ESD ALOX15 427/4885MAPK1 4138/4885HTT 264/4885
US-20180155370-A1 THERMOSETTING ALKOXYSILYL COMPOUND HAVING TWO OR MORE ALKOXYSILYL GROUPS, COMPOSITION AND CURED PRODUCT COMPRISING SAME, USE THEREOF, AND METHOD FOR PREPARING ALKOXYSILYL COMPOUND PIEZO1, FTO, ESD ALOX15 427/4885MAPK1 4138/4885HTT 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.