Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535552 | 0.87 | WDR5 (0.55) | DRD2DRD4WDR5MAOBSMN1; SMN2 | |
| SCHEMBL10715309 | 0.84 | MAPT (0.54) | SCN5ASCN9AWDR5ARCYP1A2 | |
| SCHEMBL7747269 | 0.83 | CARM1 (0.39) | CYP2C9MAOBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3716891 | 0.81 | MAOA (0.52) | SCN5ASCN9AARCYP1A2CYP2C9 | |
| SCHEMBL29349910 | 0.81 | MAOA (0.52) | SCN5ASCN9AARCYP1A2CYP2C9 | |
| SCHEMBL29924283 | 0.80 | RHEB (0.52) | SCN5ASCN9AWDR5ARCYP1A2 | |
| SCHEMBL6206121 | 0.80 | RHEB (0.52) | SCN5ASCN9AWDR5ARCYP1A2 | |
| SCHEMBL5545085 | 0.79 | AR (0.46) | SCN5ASCN9AARCYP1A2CYP2C9 | |
| SCHEMBL8966908 | 0.79 | LTA4H (0.66) | SCN5ASCN9ADRD2DRD4WDR5 | |
| SCHEMBL10876902 | 0.79 | ALDH1A1 (0.53) | DRD2DRD4WDR5SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036371-A1 | CARBONIC ACID DERIVATIVES AND THEIR USE AS ECTOPARASITICIDAL COMPOSITION | NOVARTIS AG (CH) | 2001-05-25 | — | — | WO | disclosed |