Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535429 | 0.94 | MAOB (0.52) | LTA4HMAOBALDH1A1AOC3 | |
| SCHEMBL2096245 | 0.88 | KIF11 (0.49) | MAOBALDH1A1AOC3 | |
| SCHEMBL11148692 | 0.82 | CA1 (0.52) | LTA4HMAOBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1685383 | 0.82 | CA1 (0.52) | LTA4HMAOBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL29377645 | 0.80 | LTA4H (0.50) | LTA4HMAOBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11336712 | 0.80 | RAB9A (0.57) | MAOBALDH1A1LMNAMAPTATM | |
| SCHEMBL5534895 | 0.80 | MAPK14 (0.48) | LTA4HMAOBCACNA1BMAPK14SCN9A | |
| SCHEMBL1044973 | 0.78 | LTA4H (0.50) | LTA4HMAOBALDH1A1AOC3 | |
| SCHEMBL5544769 | 0.77 | TAAR1 (0.50) | LTA4HMAOBMAPK14 | |
| SCHEMBL7747383 | 0.77 | LTA4H (0.58) | LTA4HMAOBALDH1A1AOC3CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036371-A1 | CARBONIC ACID DERIVATIVES AND THEIR USE AS ECTOPARASITICIDAL COMPOSITION | NOVARTIS AG (CH) | 2001-05-25 | — | — | WO | disclosed |