Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 8/20 | 0.51 |
| ▸ | MMP9 | P14780 | 8/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.47 |
| ▸ | MMP12 | P39900 | 3/20 | 0.47 |
| ▸ | MMP14 | P50281 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.47 |
| ▸ | HPN | P05981 | 2/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.46 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118903 | 0.89 | ALDH1A1 (0.46) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL3448321 | 0.87 | MMP9 (0.58) | MMP2MMP9ITGB3ITGA2BMMP1 | |
| SCHEMBL3448325 | 0.87 | MMP9 (0.58) | MMP2MMP9ITGB3ITGA2BMMP1 | |
| SCHEMBL11668810 | 0.87 | ITGB3 (0.49) | MMP2MMP9ITGB3ITGA2B | |
| SCHEMBL11668797 | 0.87 | ITGB3 (0.49) | MMP2MMP9ITGB3ITGA2B | |
| SCHEMBL20560096 | 0.85 | PLG (0.57) | PLGHPNST14HGFACPLAU | |
| SCHEMBL1328461 | 0.85 | PLG (0.57) | PLGHPNST14HGFACPLAU | |
| SCHEMBL2928771 | 0.85 | F2 (0.53) | F2PLGHPNST14HGFAC | |
| SCHEMBL8715885 | 0.83 | MMP9 (0.73) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL8715883 | 0.83 | MMP9 (0.73) | SLC1A3SLC1A2SLC1A1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725797-B1 | BIVALENT THROMBIN INHIBITORS | CA NAT RESEARCH COUNCIL (CA) | 2001-01-10 | — | — | EP | claimed |