Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.43 |
| ▸ | CA2 | P00918 | 11/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | MMP2 | P08253 | 6/20 | 0.36 |
| ▸ | MMP9 | P14780 | 6/20 | 0.36 |
| ▸ | MMP8 | P22894 | 4/20 | 0.36 |
| ▸ | MMP12 | P39900 | 4/20 | 0.36 |
| ▸ | MMP14 | P50281 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748705 | 0.92 | ALDH1A1 (0.38) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL7753629 | 0.83 | ITGB3 (0.47) | — | |
| SCHEMBL7748751 | 0.81 | SYK (0.42) | CA1CA12MMP2MMP9MMP8 | |
| SCHEMBL7752387 | 0.81 | MMP2 (0.44) | CA1CA2MMP2MMP9MMP8 | |
| SCHEMBL7748597 | 0.80 | ALDH1A1 (0.39) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL7752666 | 0.78 | MMP2 (0.45) | CA1CA2MMP2MMP9MMP8 | |
| SCHEMBL7748713 | 0.77 | SYK (0.40) | CA1CA12ALDH1A1POLB | |
| SCHEMBL7752670 | 0.72 | ITGAV (0.42) | CA1CA2ALDH1A1 | |
| SCHEMBL24129425 | 0.72 | CA2 (0.49) | CA1CA2CA12CA9PTPRB | |
| SCHEMBL7753684 | 0.72 | MEN1 (0.41) | CA1CA2MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |