Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.45 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | S100A9 | P06702 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573122 | 0.86 | PGR (0.50) | PGRPSIP1ARBRD4SLC22A12 | |
| SCHEMBL6577272 | 0.84 | PSIP1 (0.44) | PGRPSIP1ARBRD4SLC22A12 | |
| SCHEMBL6662088 | 0.78 | NLRP3 (0.44) | PGRPSIP1ARBRD4HPGD | |
| SCHEMBL8054362 | 0.76 | PGR (0.39) | PGRPSIP1ARBRD4SLC22A12 | |
| SCHEMBL7688191 | 0.76 | PGR (0.40) | PGRPSIP1ARBRD4SLC22A12 | |
| SCHEMBL4035205 | 0.75 | PSIP1 (0.46) | PGRPSIP1ARBRD4SLC22A12 | |
| SCHEMBL7501564 | 0.74 | PGR (0.35) | PGRPSIP1ARBRD4CA1 | |
| SCHEMBL7753456 | 0.74 | PGR (0.37) | PGRPSIP1ARBRD4SLC22A12 | |
| SCHEMBL5842931 | 0.72 | PGR (0.43) | PGRPSIP1ARBRD4SLC22A12 | |
| SCHEMBL3628472 | 0.72 | TRPV4 (0.50) | CA1CA2CA9ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070055-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | Bayer Aktiengesellschaft (DE) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052878-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |