Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | S100A9 | P06702 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577272 | 0.88 | PSIP1 (0.44) | PGRPSIP1ARSLC22A12BRD4 | |
| SCHEMBL7753799 | 0.86 | PGR (0.45) | PGRPSIP1ARSLC22A12BRD4 | |
| SCHEMBL6574292 | 0.83 | PGR (0.39) | PGRARSLC22A12TRPV4KIF11 | |
| SCHEMBL7688191 | 0.82 | PGR (0.40) | PGRPSIP1ARSLC22A12BRD4 | |
| SCHEMBL4035205 | 0.81 | PSIP1 (0.46) | PGRPSIP1ARSLC22A12BRD4 | |
| SCHEMBL6662088 | 0.79 | NLRP3 (0.44) | PGRPSIP1ARBRD4HPGD | |
| SCHEMBL5842931 | 0.78 | PGR (0.43) | PGRPSIP1ARSLC22A12BRD4 | |
| SCHEMBL8182967 | 0.77 | PSIP1 (0.44) | PGRPSIP1ARSLC22A12BRD4 | |
| SCHEMBL8054362 | 0.77 | PGR (0.39) | PGRPSIP1ARSLC22A12BRD4 | |
| SCHEMBL8902904 | 0.77 | PGR (0.43) | PGRPSIP1ARSLC22A12BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003718-B1 | METHOD FOR THE PRODUCTION OF N-(5-AMINO-2-CYANO-4-FLUORO-PHENYL)-SULPHONAMIDES | BAYER CROPSCIENCE AG (DE) | 2004-04-28 | — | — | EP | disclosed |
| US-6545154-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-08 | — | — | US | disclosed |
| US-20030040626-A1 | Method for the production of N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides and new intermediate products | HUPPERTS ACHIM (DE) | 2003-02-27 | — | — | US | disclosed |
| US-6310206-B1 | 2-AMINO-4,5-DIFLUORO-BENZONITRILE IS REACTED A SULPHONYL HALIDES; N-(2-CYANO-4,5-DIFLUORO-PHENYL)-SULPHONAMIDES (CLAIMED AS INTERMEDIATES) OBTAINED IN THE FIRST STEP ARE AMINATED WITH AMMONIA | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-30 | — | — | US | disclosed |
| EP-1003718-A1 | METHOD FOR THE PRODUCTION OF N-(5-AMINO-2-CYANO-4-FLUORO-PHENYL)-SULPHONAMIDES AND NEW INTERMEDIATE PRODUCTS | BAYER AG (DE) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999005098-A1 | METHOD FOR THE PRODUCTION OF N-(5-AMINO-2-CYANO-4-FLUORO-PHENYL)-SULPHONAMIDES AND NEW INTERMEDIATE PRODUCTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040626-A1 | Method for the production of N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides and new intermediate products | PFAS, SRM, NISCH | PGR 4825/4885PSIP1 459/4885AR 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.