SCHEMBL7754050

SCHEMBL7754050

O=[N+]([O-])c1cc(Cl)c2nonc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
TLR9 Q9NR96 5/20 0.51
NPC1 O15118 4/20 0.51
RAB9A P51151 3/20 0.51
LMNA P02545 2/20 0.51
MAPT P10636 2/20 0.51
HTT P42858 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
TP53 P04637 1/20 0.51
HPGD P15428 1/20 0.51
XBP1 P17861 1/20 0.51
MEN1 O00255 7/20 0.48
KMT2A Q03164 7/20 0.48
POLB P06746 2/20 0.48
OPRD1 P41143 2/20 0.48
OPRK1 P41145 2/20 0.48
MAPK1 P28482 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
GPR55 Q9Y2T6 1/20 0.48
GPR35 Q9HC97 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22118150 0.79 MEN1 (0.45) ALDH1A1TLR9NPC1RAB9ALMNA
SCHEMBL4746865 0.78 MEN1 (0.46) ALDH1A1TLR9NPC1RAB9ALMNA
SCHEMBL5243653 0.72 ARNT (0.45) ALDH1A1TLR9NPC1RAB9ALMNA
SCHEMBL5708771 0.71 NPC1 (0.73) ALDH1A1TLR9NPC1RAB9ALMNA
SCHEMBL5244995 0.71 MAPT (0.45) ALDH1A1NPC1RAB9AMAPTHTT
SCHEMBL28587403 0.71 TXNRD1 (0.56) ALDH1A1LMNASMN1; SMN2TP53HPGD
SCHEMBL7089706 0.69 MEN1 (0.66) ALDH1A1TLR9NPC1RAB9ALMNA
SCHEMBL887770 0.69 GPR35 (0.77) ALDH1A1NPC1RAB9ALMNAMAPT
SCHEMBL5244253 0.68 MAPT (0.50) ALDH1A1NPC1RAB9ALMNAMAPT
SCHEMBL14446368 0.68 MAPT (0.41) ALDH1A1TLR9NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001047485-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-07-05 WO disclosed